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Abstract:

Advancements in volume electron microscopy mean it is now possible to generate thousands of serial images at nanometre resolution overnight, yet the gold standard approach for data analysis remains manual segmentation by an expert microscopist, resulting in a critical research bottleneck. Although some machine learning approaches exist in this domain, we remain far from realizing the aspiration of a highly accurate, yet generic, automated analysis approach, with a major obstacle being lack of sufficient high-quality ground-truth data. To address this, we developed a novel citizen science project, Etch a Cell, to enable volunteers to manually segment the nuclear envelope (NE) of HeLa cells imaged with serial blockface scanning electron microscopy. We present our approach for aggregating multiple volunteer annotations to generate a high-quality consensus segmentation and demonstrate that data produced exclusively by volunteers can be used to train a highly accurate machine learning algorithm for automatic segmentation of the NE, which we share here, in addition to our archived benchmark data.

Abstract:

We report on the discovery and validation of a two-planet system around a bright (V = 8.85 mag) early G dwarf (1.43 $R_{\odot}$, 1.15 $M_{\odot}$, TOI 2319) using data from NASA's Transiting Exoplanet Survey Satellite (TESS). Three transit events from two planets were detected by citizen scientists in the month-long TESS light curve (sector 25), as part of the Planet Hunters TESS project. Modelling of the transits yields an orbital period of \Pb\ and radius of $3.41 _{ - 0.12 } ^ { + 0.14 }$ $R_{\oplus}$ for the inner planet, and a period in the range 19.26-35 days and a radius of $5.83 _{ - 0.14 } ^ { + 0.14 }$ $R_{\oplus}$ for the outer planet, which was only seen to transit once. Each signal was independently statistically validated, taking into consideration the TESS light curve as well as the ground-based spectroscopic follow-up observations. Radial velocities from HARPS-N and EXPRES yield a tentative detection of planet b, whose mass we estimate to be $11.56 _{ - 6.14 } ^ { + 6.58 }$ $M_{\oplus}$, and allow us to place an upper limit of $27.5$ $M_{\oplus}$ (99 per cent confidence) on the mass of planet c. Due to the brightness of the host star and the strong likelihood of an extended H/He atmosphere on both planets, this system offers excellent prospects for atmospheric characterisation and comparative planetology.

Abstract:

We use new Hubble Space Telescope (HST) images of nine Green Pea galaxies (GPGs) to study their resolved structure and color. The choice of filters, F555W and F850LP, together with the redshift of the galaxies (z ~ 0.25), minimizes the contribution of the nebular [O iii] and Hα emission lines to the broadband images. While these galaxies are typically very blue in color, our analysis reveals that it is only the dominant stellar clusters that are blue. Each GPG does clearly show the presence of at least one bright and compact star-forming region, but these are invariably superimposed on a more extended and lower surface brightness emission. Moreover, the colors of the star-forming regions are on average bluer than those of the diffuse emission, reaching up to 0.6 magnitudes bluer. Assuming that the diffuse and compact components have constant and single-burst star formation histories, respectively, the observed colors imply that the diffuse components (possibly the host galaxy of the star formation episode) have, on average, old stellar ages (>1 Gyr), while the star clusters are younger than 500 Myr. While a redder stellar component is perhaps the most plausible explanation for these results, the limitations of our current data set lead us to examine possible alternative mechanisms, particularly recombination emission processes, which are unusually prominent in systems with such strong line emission. With the available data, however, it is not possible to distinguish between these two interpretations. A substantial presence of old stars would indicate that the mechanisms allowing large escape fractions in these local galaxies may be different from those at play during the reionization epoch.