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Abstract:

Recent experiments [Banerjee et al, arXiv:1710.00492] have measured thermal conductance of the ν = 5/2 edge in a GaAs electron gas and found it to be quantized as K ≈ 5/2 (in appropriate dimensionless units). This result is unexpected, as prior numerical work predicts that the ν = 5/2 state should be the Anti-Pfaffian phase of matter, which should have quantized K = 3/2. The purpose of this paper is to propose a possible solution to this conflict: if the Majorana edge mode of the Anti-Pfaffian does not thermally equilibrate with the other edge modes, then K = 5/2 is expected. I briefly discuss a possible reason for this nonequilibration, and what should be examined further to determine if this is the case.

Abstract:

Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for chemotaxis that is valid for enzymes and other small molecules. Our theory includes both nonspecific interactions between enzyme and substrate as well as complex formation through specific binding between the enzyme and the substrate. We find that two distinct mechanisms contribute to enzyme chemotaxis: a diffusiophoretic mechanism due to the nonspecific interactions and a new type of mechanism due to binding-induced changes in the diffusion coefficient of the enzyme. The latter chemotactic mechanism points toward lower substrate concentration if the substrate enhances enzyme diffusion and toward higher substrate concentration if the substrate inhibits enzyme diffusion. For a typical enzyme, attractive phoresis and binding-induced enhanced diffusion will compete against each other. We find that phoresis dominates above a critical substrate concentration, whereas binding-induced enhanced diffusion dominates for low substrate concentration. Our results resolve an apparent contradiction regarding the direction of urease chemotaxis observed in experiments and, in general, clarify the relation between the enhanced diffusion and the chemotaxis of enzymes. Finally, we show that the competition between the two distinct chemotactic mechanisms may be used to engineer nanomachines that move toward or away from regions with a specific substrate concentration.