Ard Louis: Publications

Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

Proceedings of the National Academy of Sciences National Academy of Sciences 119:11 (2022) e2113883119

Authors:

Iain G Johnston, Kamaludin Dingle, Sam F Greenbury, Chico Q Camargo, Jonathan PK Doye, Sebastian E Ahnert, Ard A Louis

Abstract:

Significance Why does evolution favor symmetric structures when they only represent a minute subset of all possible forms? Just as monkeys randomly typing into a computer language will preferentially produce outputs that can be generated by shorter algorithms, so the coding theorem from algorithmic information theory predicts that random mutations, when decoded by the process of development, preferentially produce phenotypes with shorter algorithmic descriptions. Since symmetric structures need less information to encode, they are much more likely to appear as potential variation. Combined with an arrival-of-the-frequent mechanism, this algorithmic bias predicts a much higher prevalence of low-complexity (high-symmetry) phenotypes than follows from natural selection alone and also explains patterns observed in protein complexes, RNA secondary structures, and a gene regulatory network.

Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Chapter in Frontiers of Nanoscience, Elsevier (2022) 195-210

Reply to Ocklenburg and Mundorf: The interplay of developmental bias and natural selection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119:28 (2022) ARTN e2205299119

Authors:

Iain G Johnston, Kamaludin Dingle, Sam F Greenbury, Chico Q Camargo, Jonathan PK Doye, Sebastian E Ahnert, Ard A Louis

Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119:11 (2022) ARTN e2113883119

Authors:

Iain G Johnston, Kamaludin Dingle, Sam F Greenbury, Chico Q Camargo, Jonathan PK Doye, Sebastian E Ahnert, Ard A Louis

The interplay of supercoiling and thymine dimers in DNA

NUCLEIC ACIDS RESEARCH 50:5 (2022) ARTN gkac082

Authors:

Wilber Lim, Ferdinando Randisi, Jonathan PK Doye, Ard A Louis

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Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

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Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Reply to Ocklenburg and Mundorf: The interplay of developmental bias and natural selection

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Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

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The interplay of supercoiling and thymine dimers in DNA

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Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

Authors:

Abstract:

Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Reply to Ocklenburg and Mundorf: The interplay of developmental bias and natural selection

Authors:

Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

Authors:

The interplay of supercoiling and thymine dimers in DNA

Authors:

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